Gene Expression Profiles of Primary Breast Cancer Tissue Using cDNA Microarray
نویسندگان
چکیده
منابع مشابه
cDNA Microarray Analysis of Gene Expression Profiles Associated with Cervical Cancer.
PURPOSE The molecular pathology of cervical cancers associated with human papillomavirus infection is presently unclear. In an effort to clarify this issue, the gene expression profiles and pathogenic cellular processes of cervical cancer lesions were investigated. MATERIALS AND METHODS Cervical cancer biopsies were obtained from patients at the Department of Obstetrics and Gynecology, The Ca...
متن کاملCharacterization of gene expression profiles of normal canine retina and brain using a retinal cDNA microarray.
PURPOSE Construction of a canine retinal custom cDNA microarray for comprehensive retinal gene expression profiling and application for the identification of genes that are preferentially expressed in the retina and brain lobes using a brain pool reference tissue. METHODS A cDNA microarray was constructed utilizing clones obtained from a normalized canine retinal expressed sequence tag librar...
متن کاملCancerous Tissue Classification Using Microarray Gene Expression
In this project, we apply machine learning techniques to perform tumor vs. normal tissue classification using gene expression microarray data, which was proven to be useful for early-stage cancer diagnosis and cancer subtype identification. We compare the results of both supervised learning (k-nearest-neighbors, SVMs, boosting) and unsupervised learning (k-means clustering, hierarchical cluster...
متن کاملPersonalized chemotherapy selection for breast cancer using gene expression profiles
Choosing the optimal chemotherapy regimen is still an unmet medical need for breast cancer patients. In this study, we reanalyzed data from seven independent data sets with totally 1079 breast cancer patients. The patients were treated with three different types of commonly used neoadjuvant chemotherapies: anthracycline alone, anthracycline plus paclitaxel, and anthracycline plus docetaxel. We ...
متن کاملGene expression profiling in polycythemia vera using cDNA microarray technology.
Polycythemia vera (PV) is a myeloproliferative disorder characterized by an increased proliferation of all three myeloid lineages. The molecular pathogenesis of PV is unknown. Using cDNA microarrays comprising 6000 human genes, we studied the gene expression profile of granulocytes obtained from 11 PV patients compared with granulocytes obtained from healthy individuals. We found that 147 genes...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Korean Breast Cancer Society
سال: 2002
ISSN: 1598-3641
DOI: 10.4048/jkbcs.2002.5.4.284